Chemoinformaics analysis of 3-OCTANOL
Molecular Weight | 130.231 | nRot | 5 |
Heavy Atom Molecular Weight | 112.087 | nRig | 0 |
Exact Molecular Weight | 130.136 | nRing | 0 |
Solubility: LogS | -1.985 | nHRing | 0 |
Solubility: LogP | 2.833 | No. of Aliphatic Rings | 0 |
Acid Count | 0 | No. of Aromatic Rings | 0 |
Base Count | 0 | No. of Aliphatic Carbocycles Rings | 0 |
Atoms Count | 27 | No. of Aliphatic Hetero Cycles | 0 |
No. of Heavy Atom | 9 | No. of Aromatic Carbocycles | 0 |
nHetero | 1 | No. of Aromatic Hetero Cycles | 0 |
nBridge Head | 0 | No. Saturated Carbocycles | 0 |
No. of Hydrogen atom | 18 | No. of Saturated Hetero Cycles | 0 |
No. of Carbon atom | 8 | No. of Saturated Rings | 0 |
No. of Nitrogen atom | 0 | No. of Arom Atom | 0 |
No. of Oxygen atom | 1 | No. of Arom Bond | 0 |
nHA | 1 | APOL | 26.1643 |
nHD | 1 | BPOL | 18.0577 |
QED | 0.566 |
Synth | 2.345 |
Natural Product Likeliness | 1.429 |
NR-PPAR-gamma | 0.042 |
Lipinski | Accepted |
Pfizer | Accepted |
GSK | Accepted |
Golden Triangle | Rejected |
Pgp-inh | 0 |
Pgp-sub | 0.877 |
HIA | 0.005 |
CACO-2 | -4.25 |
MDCK | 0.0000288 |
BBB | 0.963 |
PPB | 0.664816 |
VDSS | 1.226 |
FU | 0.367271 |
CYP1A2-inh | 0.567 |
CYP1A2-sub | 0.908 |
CYP2c19-inh | 0.102 |
CYP2c19-sub | 0.768 |
CYP2c9-inh | 0.074 |
CYP2c9-sub | 0.616 |
CYP2d6-inh | 0.009 |
CYP2d6-sub | 0.206 |
CYP3a4-inh | 0.015 |
CYP3a4-sub | 0.167 |
CL | 11.971 |
T12 | 0.663 |
hERG | 0.027 |
Ames | 0.008 |
ROA | 0.025 |
SkinSen | 0.436 |
Carcinogencity | 0.085 |
EI | 0.99 |
Respiratory | 0.327 |
NR-Aromatase | 0.005 |
Antiviral | No |
Prediction | 0.94617 |