Chemoinformaics analysis of 5-Methoxypyrrolidin-2-one
| Molecular Weight | 115.132 | nRot | 1 |
| Heavy Atom Molecular Weight | 106.06 | nRig | 6 |
| Exact Molecular Weight | 115.063 | nRing | 1 |
| Solubility: LogS | 0.042 | nHRing | 1 |
| Solubility: LogP | -0.666 | No. of Aliphatic Rings | 1 |
| Acid Count | 0 | No. of Aromatic Rings | 0 |
| Base Count | 0 | No. of Aliphatic Carbocycles Rings | 0 |
| Atoms Count | 17 | No. of Aliphatic Hetero Cycles | 1 |
| No. of Heavy Atom | 8 | No. of Aromatic Carbocycles | 0 |
| nHetero | 3 | No. of Aromatic Hetero Cycles | 0 |
| nBridge Head | 0 | No. Saturated Carbocycles | 0 |
| No. of Hydrogen atom | 9 | No. of Saturated Hetero Cycles | 1 |
| No. of Carbon atom | 5 | No. of Saturated Rings | 1 |
| No. of Nitrogen atom | 1 | No. of Arom Atom | 0 |
| No. of Oxygen atom | 2 | No. of Arom Bond | 0 |
| nHA | 2 | APOL | 17.0551 |
| nHD | 1 | BPOL | 12.2029 |
| QED | 0.517 |
| Synth | 3.447 |
| Natural Product Likeliness | 1.467 |
| NR-PPAR-gamma | 0.009 |
| Lipinski | Accepted |
| Pfizer | Accepted |
| GSK | Accepted |
| Golden Triangle | Rejected |
| Pgp-inh | 0 |
| Pgp-sub | 0.264 |
| HIA | 0.007 |
| CACO-2 | -4.335 |
| MDCK | 0.0000408 |
| BBB | 0.899 |
| PPB | 0.075035 |
| VDSS | 0.861 |
| FU | 0.87484 |
| CYP1A2-inh | 0.023 |
| CYP1A2-sub | 0.358 |
| CYP2c19-inh | 0.03 |
| CYP2c19-sub | 0.629 |
| CYP2c9-inh | 0.017 |
| CYP2c9-sub | 0.181 |
| CYP2d6-inh | 0.01 |
| CYP2d6-sub | 0.164 |
| CYP3a4-inh | 0.006 |
| CYP3a4-sub | 0.177 |
| CL | 6.768 |
| T12 | 0.78 |
| hERG | 0.011 |
| Ames | 0.055 |
| ROA | 0.019 |
| SkinSen | 0.254 |
| Carcinogencity | 0.048 |
| EI | 0.241 |
| Respiratory | 0.018 |
| NR-Aromatase | 0.004 |
| Antiviral | No |
| Prediction | 0.967727 |