Chemoinformaics analysis of Costic acid
Molecular Weight | 234.339 | nRot | 2 |
Heavy Atom Molecular Weight | 212.163 | nRig | 14 |
Exact Molecular Weight | 234.162 | nRing | 2 |
Solubility: LogS | -2.965 | nHRing | 0 |
Solubility: LogP | 3.003 | No. of Aliphatic Rings | 2 |
Acid Count | 1 | No. of Aromatic Rings | 0 |
Base Count | 0 | No. of Aliphatic Carbocycles Rings | 2 |
Atoms Count | 39 | No. of Aliphatic Hetero Cycles | 0 |
No. of Heavy Atom | 17 | No. of Aromatic Carbocycles | 0 |
nHetero | 2 | No. of Aromatic Hetero Cycles | 0 |
nBridge Head | 0 | No. Saturated Carbocycles | 2 |
No. of Hydrogen atom | 22 | No. of Saturated Hetero Cycles | 0 |
No. of Carbon atom | 15 | No. of Saturated Rings | 2 |
No. of Nitrogen atom | 0 | No. of Arom Atom | 0 |
No. of Oxygen atom | 2 | No. of Arom Bond | 0 |
nHA | 1 | APOL | 41.3234 |
nHD | 1 | BPOL | 22.9386 |
QED | 0.583 |
Synth | 4.071 |
Natural Product Likeliness | 2.84 |
NR-PPAR-gamma | 0.036 |
Lipinski | Accepted |
Pfizer | Rejected |
GSK | Accepted |
Golden Triangle | Accepted |
Pgp-inh | 0.001 |
Pgp-sub | 0 |
HIA | 0.005 |
CACO-2 | -5.036 |
MDCK | 0.0000166 |
BBB | 0.032 |
PPB | 0.906356 |
VDSS | 0.318 |
FU | 0.094197 |
CYP1A2-inh | 0.068 |
CYP1A2-sub | 0.393 |
CYP2c19-inh | 0.03 |
CYP2c19-sub | 0.079 |
CYP2c9-inh | 0.289 |
CYP2c9-sub | 0.36 |
CYP2d6-inh | 0.012 |
CYP2d6-sub | 0.429 |
CYP3a4-inh | 0.028 |
CYP3a4-sub | 0.146 |
CL | 1.496 |
T12 | 0.553 |
hERG | 0.026 |
Ames | 0.035 |
ROA | 0.28 |
SkinSen | 0.338 |
Carcinogencity | 0.388 |
EI | 0.984 |
Respiratory | 0.953 |
NR-Aromatase | 0.807 |
Antiviral | Yes |
Prediction | 0.926368 |