Chemoinformaics analysis of SHYOBUNONE
Molecular Weight | 220.356 | nRot | 3 |
Heavy Atom Molecular Weight | 196.164 | nRig | 9 |
Exact Molecular Weight | 220.183 | nRing | 1 |
Solubility: LogS | -4.72 | nHRing | 0 |
Solubility: LogP | 3.987 | No. of Aliphatic Rings | 1 |
Acid Count | 0 | No. of Aromatic Rings | 0 |
Base Count | 0 | No. of Aliphatic Carbocycles Rings | 1 |
Atoms Count | 40 | No. of Aliphatic Hetero Cycles | 0 |
No. of Heavy Atom | 16 | No. of Aromatic Carbocycles | 0 |
nHetero | 1 | No. of Aromatic Hetero Cycles | 0 |
nBridge Head | 0 | No. Saturated Carbocycles | 1 |
No. of Hydrogen atom | 24 | No. of Saturated Hetero Cycles | 0 |
No. of Carbon atom | 15 | No. of Saturated Rings | 1 |
No. of Nitrogen atom | 0 | No. of Arom Atom | 0 |
No. of Oxygen atom | 1 | No. of Arom Bond | 0 |
nHA | 1 | APOL | 41.855 |
nHD | 0 | BPOL | 24.945 |
QED | 0.504 |
Synth | 4.176 |
Natural Product Likeliness | 2.495 |
NR-PPAR-gamma | 0.003 |
Lipinski | Accepted |
Pfizer | Rejected |
GSK | Accepted |
Golden Triangle | Accepted |
Pgp-inh | 0.854 |
Pgp-sub | 0.001 |
HIA | 0.011 |
CACO-2 | -4.521 |
MDCK | 0.0000156 |
BBB | 0.049 |
PPB | 0.956665 |
VDSS | 1.484 |
FU | 0.0395197 |
CYP1A2-inh | 0.263 |
CYP1A2-sub | 0.72 |
CYP2c19-inh | 0.704 |
CYP2c19-sub | 0.92 |
CYP2c9-inh | 0.451 |
CYP2c9-sub | 0.146 |
CYP2d6-inh | 0.495 |
CYP2d6-sub | 0.119 |
CYP3a4-inh | 0.888 |
CYP3a4-sub | 0.789 |
CL | 3.008 |
T12 | 0.207 |
hERG | 0.013 |
Ames | 0.039 |
ROA | 0.326 |
SkinSen | 0.147 |
Carcinogencity | 0.215 |
EI | 0.154 |
Respiratory | 0.969 |
NR-Aromatase | 0.035 |
Antiviral | Yes |
Prediction | 0.918465 |