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सीएसआईआर - उत्तर पूर्व विज्ञान एवं प्रौद्योगिकी संस्थान
CSIR-North East Institute of Science and Technology

Bio-Data

Particulars of organization, functions and duties

Dr Prasenjit Manna

Dr Prasenjit Manna

Designation : Scientist E

ID. No.: 1294

Email id : pmanna2012@gmail.com, pmanna@neist.res.in


Research Interest

MOLECULAR NUTRITION AND ENDOCRINOLOGY; HEALTH BENEFITS OF FERMENTED FOODS; ETHNOPHARMACOLOGY; SMART MATERIALS FOR GENE/DRUG DELIVERY AND HEALTHCARE DIAGNOSTIC.

Projects(Ongoing & Completed)

  • Vitamin K as an adjuvant therapy for the prevention of insulin resistance and vascular inflammation in diabetes (PI, COMPLETED).
  • A novel therapeutic against metabolic syndrome via activation of coagulation unrelated vitamin K dependent proteins (PI COMPLETED).
  • Ethnomedicinal North-Eastern Spice (Allium spp.) against Respiratory Viral Infections: Efficacy, Bioactives, and Mechanistic Insight (ONGOING) (PI).
  • Ethnomedicinal North-Eastern Spice (Allium spp.) against Respiratory Viral Infections: Efficacy, Bioactives, and Mechanistic Insight (ONGOING) (PI).

List of Publications

  • Loying R, Lamyanba L, Borah A, Thokchom R, Cukhamu V, Barman H, Sharmah B, Afzal NU, Kabir ME, Das AM, Kalita J, Mukherjee PK, Sharma N, Manna P*. Endotoxin (lipopolysaccharide)-induced inflammation in albino rat and macrophages (RAW 264.7): Piper mullesua leaf extract as promising therapeutic against inflammatory pathophysiology via SOCS1 activation and phospho-NF-κB/JAK1/STAT1 inhibition. Inflammopharmacology. 2025;33(5):2749-2768.
  • Das D, Afzal NU, Wann SB, Kalita J, Manna P*. A ~24 kDa protein isolated from protein isolates of Hawaijar, popular fermented soy food of North East India exhibited promising antidiabetic potential via stimulating PI3K/AKT/GLUT4 signaling pathway of muscle glucose metabolism. International Journal of Biological Macromolecules. 2023;224:1025-1039.
  • Sarkar S, Sadhukhan P, Das D, Basyach P, Das J, Das MR, Saikia L, Wann SB, Kalita J, Sil PC, Manna, P*. Glucose-Sensitive Delivery of Vitamin K by Using Surface-Functionalized, Dextran-Capped Mesoporous Silica Nanoparticles To Alleviate Hyperglycemia. ACS Applied Materials & Interfaces. 2022;14:26489-26500.
  • Das D, Sarkar S, Dihingia A, Afzal NU, Wann SB, Kalita J, Dewanjee S, Manna P*. A popular fermented soybean food of Northeast India exerted promising antihyperglycemic potential via stimulating PI3K/AKT/AMPK/GLUT4 signaling pathways and regulating muscle glucose metabolism in type 2 diabetes. Journal of Food Biochemistry. 2022;7:e14385. (This work was highlighted as “Fermented Soybean Foods: Managing diabetes” in the prestigious journal Current Science under News Section (2022;123(7):0837-0838).
  • Dihingia A, Ozah D, Bora T, Kalita J, Manna P*. Gamma-glutamyl-carboxylated Gas6 mediates positive role of vitamin K on lowering hyperglycemia in type 2 diabetes. Annals of the New York Academy of Sciences 2020,1462:104 117.